With eight days remaining in Trump's term, the House will vote on Wednesday on an article of impeachment accusing the Republican of inciting insurrection in a speech to his followers last week before a mob of them stormed the Capitol, leaving five dead.
That would trigger a trial in the still Republican-controlled Senate, although it was unclear whether enough time or political appetite remained to expel Trump.
Democrats moved forward on an impeachment vote after a effort to persuade Vice President Mike Pence to invoke the 25th Amendment of the U.S. Constitution to remove Trump was rejected by Pence on Tuesday evening.
"I do not believe that such a course of action is in the best interest of our Nation or consistent with our Constitution," Pence said in a letter to House Speaker Nancy Pelosi.
Despite the letter, the House passed a resolution formally calling on Pence to act. The final vote was 223-205 in favor.
While that was occurring, Trump's iron grip on his party was showing further signs of slipping as at least four Republicans, including a member of the House leadership, said they would vote for his second impeachment - a prospect no president before Trump has faced.